| |
|
|
 | Acceso al texto completo restringido a Biblioteca INIA La Estanzuela. Por información adicional contacte bib_le@inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA La Estanzuela. |
|
Fecha : |
31/05/2022 |
|
Actualizado : |
02/12/2022 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Autor : |
COSTA, M.; SARAVIA, A.; UBIOS, D.; LORES, L.; DA COSTA, V.; FESTARI, M.F.; LANDEIRA, M.; RODRÍGUEZ-ZRAQUIA, S.A.; BANCHERO, G.; FREIRE, T. |
|
Afiliación : |
MONIQUE COSTA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DIEGO UBIOS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.; PABLO LORES, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; VALERIA DA COSTA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; MARÍA FLORENCIA FESTARI, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; MERCEDES LANDEIRA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; SANTIAGO A. RODRÍGUEZ-ZRAQUIA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; GEORGGET ELIZABETH BANCHERO HUNZIKER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; TERESA FREIRE, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay. |
|
Título : |
Liver function markers and haematological dynamics during acute and chronic phases of experimental Fasciola hepatica infection in cattle treated with triclabendazole. |
|
Fecha de publicación : |
2022 |
|
Fuente / Imprenta : |
Experimental Parasitology, July 2022, Volume 238, e108285. doi://doi.org/10.1016/j.exppara.2022.108285 |
|
ISSN : |
0014-4894 |
|
DOI : |
10.1016/j.exppara.2022.108285 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received 13 September 2021; Revised 24 May 2022; Accepted 27 May 2022; Available online 30 May 2022; Published July 2022. -- Corresponding author : Freire, T.; Facultad de Medicina, Departamento de Inmunobiología. Gral. Flores 2125, Montevideo, Uruguay; email:tfreire@fmed.edu.uy -- |
|
Contenido : |
Abstract:
Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis causes huge economic losses worldwide, reducing animal fertility, milk production, weight gain and condemnation of livers. In spite of the availability of drugs, such as triclabendazole (TCZ), for the treatment of fasciolosis, they do not necessarily prevent liver damage or parasite reinfection and can eventually increase parasite resistance. The aim of this research was to relate the hepatic function, haematological parameters, leukocyte counts in circulation and parasite egg shedding during F. hepatica acute and chronic phases of infection in cattle as well as to determine how these parameters change with TCZ-treatment of chronically infected cattle. Our results show that increased levels of serum aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were detected in early stages of the experimental infection. Moreover, high circulating eosinophil count and plateletcrit levels were correlated with fluke number in livers from infected cattle. On the other hand, although TCZ-treatment in the chronic phase of infection reduced parasite burden and damage in the liver, it was not able to completely avoid them. In conclusion, our work sheds light into the physiopathological mechanisms induced during fluke infection in cattle, revealing the complexity of the host response to the infection, together with the effects of TCZ-treatment in chronically infected animals. © 2022 MenosAbstract:
Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis causes huge economic losses worldwide, reducing animal fertility, milk production, weight gain and condemnation of livers. In spite of the availability of drugs, such as triclabendazole (TCZ), for the treatment of fasciolosis, they do not necessarily prevent liver damage or parasite reinfection and can eventually increase parasite resistance. The aim of this research was to relate the hepatic function, haematological parameters, leukocyte counts in circulation and parasite egg shedding during F. hepatica acute and chronic phases of infection in cattle as well as to determine how these parameters change with TCZ-treatment of chronically infected cattle. Our results show that increased levels of serum aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were detected in early stages of the experimental infection. Moreover, high circulating eosinophil count and plateletcrit levels were correlated with fluke number in livers from infected cattle. On the other hand, although TCZ-treatment in the chronic phase of infection reduced parasite burden and damage in the liver, it was not able to completely avoid them. In conclusion, our work sheds light into the physiopathological mechanisms induced during fluke infection in cattle, revealing the complexity of the host response to ... Presentar Todo |
|
Palabras claves : |
Fasciola hepatica; Fasciolosis; Fluke; LIVER; PLATAFORMA DE SALUD ANIMAL; Triclabendazole. |
|
Asunto categoría : |
L73 Enfermedades de los animales |
|
Marc : |
LEADER 02950naa a2200337 a 4500
001 1063184
005 2022-12-02
008 2022 bl uuuu u00u1 u #d
022 $a0014-4894
024 7 $a10.1016/j.exppara.2022.108285$2DOI
100 1 $aCOSTA, M.
245 $aLiver function markers and haematological dynamics during acute and chronic phases of experimental Fasciola hepatica infection in cattle treated with triclabendazole.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 13 September 2021; Revised 24 May 2022; Accepted 27 May 2022; Available online 30 May 2022; Published July 2022. -- Corresponding author : Freire, T.; Facultad de Medicina, Departamento de Inmunobiología. Gral. Flores 2125, Montevideo, Uruguay; email:tfreire@fmed.edu.uy --
520 $aAbstract: Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis causes huge economic losses worldwide, reducing animal fertility, milk production, weight gain and condemnation of livers. In spite of the availability of drugs, such as triclabendazole (TCZ), for the treatment of fasciolosis, they do not necessarily prevent liver damage or parasite reinfection and can eventually increase parasite resistance. The aim of this research was to relate the hepatic function, haematological parameters, leukocyte counts in circulation and parasite egg shedding during F. hepatica acute and chronic phases of infection in cattle as well as to determine how these parameters change with TCZ-treatment of chronically infected cattle. Our results show that increased levels of serum aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were detected in early stages of the experimental infection. Moreover, high circulating eosinophil count and plateletcrit levels were correlated with fluke number in livers from infected cattle. On the other hand, although TCZ-treatment in the chronic phase of infection reduced parasite burden and damage in the liver, it was not able to completely avoid them. In conclusion, our work sheds light into the physiopathological mechanisms induced during fluke infection in cattle, revealing the complexity of the host response to the infection, together with the effects of TCZ-treatment in chronically infected animals. © 2022
653 $aFasciola hepatica
653 $aFasciolosis
653 $aFluke
653 $aLIVER
653 $aPLATAFORMA DE SALUD ANIMAL
653 $aTriclabendazole
700 1 $aSARAVIA, A.
700 1 $aUBIOS, D.
700 1 $aLORES, L.
700 1 $aDA COSTA, V.
700 1 $aFESTARI, M.F.
700 1 $aLANDEIRA, M.
700 1 $aRODRÍGUEZ-ZRAQUIA, S.A.
700 1 $aBANCHERO, G.
700 1 $aFREIRE, T.
773 $tExperimental Parasitology, July 2022, Volume 238, e108285. doi://doi.org/10.1016/j.exppara.2022.108285
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA La Estanzuela (LE) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
|
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas; INIA Treinta y Tres. |
|
Fecha actual : |
17/12/2021 |
|
Actualizado : |
20/12/2021 |
|
Tipo de producción científica : |
Serie Técnica |
|
Autor : |
SALDAIN, N.E.; MARCHESI, C.; ROSAS, J.E.; PEREIRA, A.L.; SARAVIA, H.; MESONES, B. (Ed.). |
|
Afiliación : |
NÉSTOR ELIO SALDAIN CROCCE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CLAUDIA ELIZABETH MARCHESI GYERMAN, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JUAN EDUARDO ROSAS CAISSIOLS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANA LAURA PEREIRA AMATO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; HORACIO SARAVIA DIAZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; BELKY YANEL MESONES PEREIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
|
Título : |
Manejo sustentable del arroz resistente a las imidazolinonas. |
|
Fecha de publicación : |
2021 |
|
Fuente / Imprenta : |
Montevideo (Uruguay): INIA, 2021. Doi: http://doi.org/10.35676/INIA/ST.260 |
|
Páginas : |
88 p. |
|
Serie : |
(INIA Serie Técnica; 260). |
|
ISSN : |
1688-9266 |
|
DOI : |
10.35676/INIA/ST.260 |
|
Idioma : |
Español |
|
Contenido : |
En la siguiente publicación se consolida el conocimiento generado en el marco de la ejecución de varios proyectos relacionados con la utilización de los arroces
resistentes a las imidazolinonas, más la experiencia de campo obtenida por los usuarios y las medidas de cuidado de la tecnología recomendada por la empresa
BASF. El objetivo de esta publicación es exponer lo aprendido respecto a esta tecnología y ahondar en la elaboración de pautas claras para promover un manejo sustentable de la misma. |
|
Thesagro : |
ARROZ; CONTROL DE MALEZAS; IMAZAPiC; IMAZAPIR; IMIDAZOLINONAS. |
|
Asunto categoría : |
F01 Cultivo |
|
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16138/1/st-260-2021.pdf
|
|
Marc : |
LEADER 01290nam a2200277 a 4500
001 1062585
005 2021-12-20
008 2021 bl uuuu u00u1 u #d
022 $a1688-9266
024 7 $a10.35676/INIA/ST.260$2DOI
100 1 $aSALDAIN, N.E.
245 $aManejo sustentable del arroz resistente a las imidazolinonas.$h[electronic resource]
260 $aMontevideo (Uruguay): INIA, 2021. Doi: http://doi.org/10.35676/INIA/ST.260$c2021
300 $a88 p.
490 $a(INIA Serie Técnica; 260).
520 $aEn la siguiente publicación se consolida el conocimiento generado en el marco de la ejecución de varios proyectos relacionados con la utilización de los arroces resistentes a las imidazolinonas, más la experiencia de campo obtenida por los usuarios y las medidas de cuidado de la tecnología recomendada por la empresa BASF. El objetivo de esta publicación es exponer lo aprendido respecto a esta tecnología y ahondar en la elaboración de pautas claras para promover un manejo sustentable de la misma.
650 $aARROZ
650 $aCONTROL DE MALEZAS
650 $aIMAZAPiC
650 $aIMAZAPIR
650 $aIMIDAZOLINONAS
700 1 $aMARCHESI, C.
700 1 $aROSAS, J.E.
700 1 $aPEREIRA, A.L.
700 1 $aSARAVIA, H.
700 1 $aMESONES, B.
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
